Diethyl Cyanomethylphosphonate CAS 2537-48-6 Purity >99.0% (GC) Factory High Quality
Manufacturer Supply With High Quality, Commercial Production
Chemical Name: Diethyl Cyanomethylphosphonate CAS: 2537-48-6
Chemical Name | Diethyl Cyanomethylphosphonate |
Synonyms | Cyanomethylphosphonic Acid Diethyl Ester |
CAS Number | 2537-48-6 |
CAT Number | RF-PI1252 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C6H12NO3P |
Molecular Weight | 177.14 |
Boiling Point | 101.0~102.0℃/0.4 mm Hg(lit.) |
Density | 1.095 g/ml at 25℃ (lit.) |
Refractive Index | N20/D 1.431~1.435 |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | Colorless Transparent Liquid |
Purity / Analysis Method | >99.0% (GC) |
Moisture (K.F) | <0.50% |
Acid Value (mgKOH/g) | <2.00 |
Total Impurities | <1.00% |
Test Standard | Enterprise Standard |
Usage | Pharmaceutical Intermediates; Horner-Emmons Reagents |
Package: Bottle, 25kg/Barrel or 200kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.
Diethyl Cyanomethylphosphonate (CAS: 2537-48-6) is used as an intermediate in Horner-Emmons reaction for the synthesis of substituted nitriles and their amide and heterocyclic derivatives. It is known as a modified Wittig reagent used in the preparation of alpha, beta-unsaturated nitriles from ketones or aldehydes like 3-hydroxy-3-methylbutanal. It reacts with epoxides and nitrones to prepare cyano-substituted cyclopropanes and aziridines respectively. It is actively involved in the synthesis of alpha-arylated alkanenitriles via reaction with aryl iodides in presence of CuI.